ASSOCIATIONS BETWEEN CYP2C8 RS10509681 AND RS11572080 GENE POLYMORPHISMS AND AGE-RELATED MACULAR DEGENERATION

Associations between CYP2C8 rs10509681 and rs11572080 gene polymorphisms and age-related macular degeneration

Background.Age-related macular degeneration (AMD) is the most common cause of irreversible visual loss in industrialized countries.Early symptoms of AMD include drusen and changes in retinal pigment epithelium.However, the etiology of AMD and drusen formation is not fully understood.Recent studies suggest that CYP2C8-related metabolic processes mig

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A Numerical Study of Sub-Millisecond Integrated Mix-and-Inject Microfluidic Devices for Sample Delivery at Synchrotron and XFELs

Microfluidic devices which integrate both rapid mixing and liquid jetting for sample delivery are an emerging solution for studying molecular dynamics via X-ray diffraction.Here we use finite element modelling to investigate the efficiency and time-resolution achievable using microfluidic mixers within the parameter range required for producing sta

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